MDAiRE™
Mdairre RXR Retinol Anti-Aging Serum
Mdairre RXR Retinol Anti-Aging Serum
“My goal is to provide my patients with the highest quality, scientifically-backed solutions to support their wellness journey. Each product is formulated with that same commitment to excellence and efficacy.”
Learn more about Dr. Piazza →Couldn't load pickup availability
Unlock Radiant Skin with RXR Retinol Anti-Aging Serum
MDAiRE™'s RXR Retinol Anti-Aging Serum helps promote cell turnover to diminish the appearance of fine lines, wrinkles, uneven skin tone, and blemishes. Our active retinol is encapsulated in a solid lipid, resulting in an anti-inflammatory and anti-irritant formula, which can be used every morning and evening. Using Retinol can make skin sensitive to the sun and UV damage because it is a strong exfoliant.
Available in 30ml and 15ml sizes
KEY INGREDIENTS
- Vitamin A (Retinol) : Promotes cellular turnover and stimulates collagen synthesis to diminish the appearance of fine lines and wrinkles.
- CoQ10: Powerful antioxidant to protect from environmental stressors and induction of collagen synthesis
- Polypodium Leucotomos: A natural plant based extract derived from fern leaves that protects DNA from the harmful effects of UV light and environmental pollutants.
- Tripeptide-5: Stimulates synthesis of collagen and elastin to smooth and firm skin.
*Cruelty Free Product made with clean ingredients. Free of parabens, fragrance, and phthalates. *
What is Retinol and How Does it Work?
Retinol is a powerful form of vitamin A that significantly improves skin texture and reduces visible signs of aging. It stimulates skin cell turnover while promoting collagen production, which leads to smoother skin and a more youthful appearance. However, its effectiveness is maximized when combined with other nourishing ingredients in RXR's formulation, ensuring your skin benefits from hydration as well.
Benefits of Using RXR Retinol Anti-Aging Serum
This serum is designed to combat fine lines, wrinkles, and uneven skin tone. Many users notice an immediate improvement in skin texture just after a few applications, making it a must-have in any skincare routine. Additionally, because it targets multiple skin concerns, RXR Retinol simplifies your regimen, allowing you to enjoy noticeable results without an extensive lineup of products.
How to Incorporate the Serum into Your Skincare Routine
To achieve optimal results, apply RXR Retinol Anti-Aging Serum in the evening after cleansing. Start with a small amount to allow your skin to build tolerance. Additionally, remember to apply sunscreen during the day, as retinol can make your skin more sensitive to the sun. Follow this simple routine, and you'll soon see why retinol is revered in skincare.

The Piazza Protocols
Hand-selected by board-certified plastic surgeon Dr. Rocco Piazza, MD, FACS, to meet the highest standards in medical-grade skincare.
🛡️ Board-Certified Plastic Surgeon
🔬 Backed by Clinical Expertise & Research
Advanced Retinol Protocol
Reduce fine lines and improve skin texture through medical-grade retinoid therapy.
Brightening Complex Protocol
Target dark spots and uneven tone with clinical-strength brightening agents.
Clinical Acne Control Protocol
Clear active breakouts and prevent future acne with medical-grade formulations.
Advanced Retinol Protocol
Skin Preparation
Begin with gentle cleanser and barrier repair serum to prepare skin for active treatment.
Retinol Introduction
Introduce 0.25% retinol 2-3 times per week, monitoring for tolerance.
Gradual Increase
Increase frequency to nightly application as tolerated.
Strength Advancement
Progress to 0.5% retinol formulation for enhanced results.
Maintenance Phase
Continue nightly application with quarterly clinical assessments.
Brightening Complex Protocol
Assessment & Prep
Clinical photography and baseline assessment with gentle exfoliation.
Active Treatment
Apply brightening serum with hydroquinone alternative twice daily.
Enhancement Phase
Add vitamin C serum in morning routine for synergistic effects.
Progress Evaluation
Clinical reassessment and protocol adjustment as needed.
Long-term Maintenance
Continue maintenance regimen with SPF 50+ daily protection.
Clinical Acne Control Protocol
Barrier Restoration
Gentle cleansing and barrier support to prepare for active treatment.
Benzoyl Peroxide Introduction
Begin 2.5% benzoyl peroxide application every other evening.
Salicylic Acid Addition
Add 2% salicylic acid serum in morning routine for pore refinement.
Retinoid Integration
Introduce retinoid 2-3 times weekly for enhanced cell turnover.
Maintenance & Prevention
Continue full protocol with monthly clinical monitoring.