The Piazza Center for Plastic Surgery & Advanced Skincare
EXO LIPS™ Lip Balm for Lip Lines & Perioral Wrinkles
EXO LIPS™ Lip Balm for Lip Lines & Perioral Wrinkles
“My goal is to provide my patients with the highest quality, scientifically-backed solutions to support their wellness journey. Each product is formulated with that same commitment to excellence and efficacy.”
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EXO LIPS™ Hydra Healing Lip Balm with eXo³ Exosomes®
EXO LIPS™ is a regenerative lip treatment designed to visibly improve lip lines, perioral wrinkles, and fine lines around the lips while delivering an immediate feeling of deep hydration. Because lips lack oil glands and experience constant movement, lip lines are often one of the earliest and most noticeable signs of aging.
Powered by Exoceuticals® patented eXo³ Exosomes® and rich, nourishing lipids, EXO LIPS™ provides fast-absorbing moisture support to help lips feel soft, smooth, and supple—without a greasy finish.
What It Helps Improve
- Lip lines and fine vertical wrinkles
- Perioral wrinkles and the look of aging around the mouth
- Dry, cracked, or dehydrated lips
- Loss of smoothness and suppleness
- Aging lips prone to thinning and creasing
Texture
Silky gel-balm texture that melts into the lips to deliver lasting hydration—comfortable, non-sticky, and easy to reapply.
How to Use
Apply generously to lips throughout the day as needed. May also be applied to the perioral area to help soften the appearance of fine lines around the lips.
Key Ingredients
eXo³ Exosomes®
Clinically engineered extracellular vesicles that support cellular communication and skin regeneration—helping improve the appearance of lip lines and support long-term lip health.
- Supports smoother-looking lips
- Helps improve the appearance of fine lines
- Supports long-term lip comfort and resilience
Squalane
A skin-identical lipid that helps deeply hydrate and support the lip barrier—ideal for dry lips and dehydration-related lip lines.
- Helps restore moisture to dry lips
- Supports a softer, smoother look
- Helps reduce moisture loss
Nourishing Plant Oils + Vitamin E
Organic avocado, argan, and marula oils plus vitamin E help replenish lipids, improve suppleness, and protect against dryness.
- Helps improve softness and flexibility
- Supports a smooth, conditioned feel
- Helps protect against environmental dryness
Full Ingredients
Polyisobutylene, Caprylic/Capric Triglyceride, Squalane, Synthetic Beeswax (Non-Animal, Naturally Derived), 12-Hydroxystearic Acid, Euphorbia Cerifera (Candelilla) Wax, Glyceryl Adipate, Glyceryl Stearate, Human Adipose Stromal Cell Exosome (eXo³ Exosomes®), Natural Vanilla, Persea Gratissima (Avocado) Oil (Organic), Argania Spinosa Kernel (Argan) Oil (Organic), Sclerocarya Birrea Seed Oil (Marula Oil) (Organic), Tocopherol (Vitamin E)

The Piazza Protocols
Hand-selected by board-certified plastic surgeon Dr. Rocco Piazza, MD, FACS, to meet the highest standards in medical-grade skincare.
🛡️ Board-Certified Plastic Surgeon
🔬 Backed by Clinical Expertise & Research
Advanced Retinol Protocol
Reduce fine lines and improve skin texture through medical-grade retinoid therapy.
Brightening Complex Protocol
Target dark spots and uneven tone with clinical-strength brightening agents.
Clinical Acne Control Protocol
Clear active breakouts and prevent future acne with medical-grade formulations.
Advanced Retinol Protocol
Skin Preparation
Begin with gentle cleanser and barrier repair serum to prepare skin for active treatment.
Retinol Introduction
Introduce 0.25% retinol 2-3 times per week, monitoring for tolerance.
Gradual Increase
Increase frequency to nightly application as tolerated.
Strength Advancement
Progress to 0.5% retinol formulation for enhanced results.
Maintenance Phase
Continue nightly application with quarterly clinical assessments.
Brightening Complex Protocol
Assessment & Prep
Clinical photography and baseline assessment with gentle exfoliation.
Active Treatment
Apply brightening serum with hydroquinone alternative twice daily.
Enhancement Phase
Add vitamin C serum in morning routine for synergistic effects.
Progress Evaluation
Clinical reassessment and protocol adjustment as needed.
Long-term Maintenance
Continue maintenance regimen with SPF 50+ daily protection.
Clinical Acne Control Protocol
Barrier Restoration
Gentle cleansing and barrier support to prepare for active treatment.
Benzoyl Peroxide Introduction
Begin 2.5% benzoyl peroxide application every other evening.
Salicylic Acid Addition
Add 2% salicylic acid serum in morning routine for pore refinement.
Retinoid Integration
Introduce retinoid 2-3 times weekly for enhanced cell turnover.
Maintenance & Prevention
Continue full protocol with monthly clinical monitoring.