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The Piazza Center for Plastic Surgery & Advanced Skincare

EXO LIPS™ Lip Balm for Lip Lines & Perioral Wrinkles

EXO LIPS™ Lip Balm for Lip Lines & Perioral Wrinkles

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Dr. P

Selected by an Expert

Dr. Rocco C. Piazza

Board-Certified Plastic Surgeon

“My goal is to provide my patients with the highest quality, scientifically-backed solutions to support their wellness journey. Each product is formulated with that same commitment to excellence and efficacy.”

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EXO LIPS™ Hydra Healing Lip Balm with eXo³ Exosomes®

EXO LIPS™ is a regenerative lip treatment designed to visibly improve lip lines, perioral wrinkles, and fine lines around the lips while delivering an immediate feeling of deep hydration. Because lips lack oil glands and experience constant movement, lip lines are often one of the earliest and most noticeable signs of aging.

Powered by Exoceuticals® patented eXo³ Exosomes® and rich, nourishing lipids, EXO LIPS™ provides fast-absorbing moisture support to help lips feel soft, smooth, and supple—without a greasy finish.


What It Helps Improve

  • Lip lines and fine vertical wrinkles
  • Perioral wrinkles and the look of aging around the mouth
  • Dry, cracked, or dehydrated lips
  • Loss of smoothness and suppleness
  • Aging lips prone to thinning and creasing

Texture

Silky gel-balm texture that melts into the lips to deliver lasting hydration—comfortable, non-sticky, and easy to reapply.


How to Use

Apply generously to lips throughout the day as needed. May also be applied to the perioral area to help soften the appearance of fine lines around the lips.


Key Ingredients

eXo³ Exosomes®

Clinically engineered extracellular vesicles that support cellular communication and skin regeneration—helping improve the appearance of lip lines and support long-term lip health.

  • Supports smoother-looking lips
  • Helps improve the appearance of fine lines
  • Supports long-term lip comfort and resilience

Squalane

A skin-identical lipid that helps deeply hydrate and support the lip barrier—ideal for dry lips and dehydration-related lip lines.

  • Helps restore moisture to dry lips
  • Supports a softer, smoother look
  • Helps reduce moisture loss

Nourishing Plant Oils + Vitamin E

Organic avocado, argan, and marula oils plus vitamin E help replenish lipids, improve suppleness, and protect against dryness.

  • Helps improve softness and flexibility
  • Supports a smooth, conditioned feel
  • Helps protect against environmental dryness

Full Ingredients

Polyisobutylene, Caprylic/Capric Triglyceride, Squalane, Synthetic Beeswax (Non-Animal, Naturally Derived), 12-Hydroxystearic Acid, Euphorbia Cerifera (Candelilla) Wax, Glyceryl Adipate, Glyceryl Stearate, Human Adipose Stromal Cell Exosome (eXo³ Exosomes®), Natural Vanilla, Persea Gratissima (Avocado) Oil (Organic), Argania Spinosa Kernel (Argan) Oil (Organic), Sclerocarya Birrea Seed Oil (Marula Oil) (Organic), Tocopherol (Vitamin E)

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The Piazza Protocols

Hand-selected by board-certified plastic surgeon Dr. Rocco Piazza, MD, FACS, to meet the highest standards in medical-grade skincare.

🛡️ Board-Certified Plastic Surgeon
🔬 Backed by Clinical Expertise & Research

DISCOVER OUR PHILOSOPHY
Anti-Aging

Advanced Retinol Protocol

Reduce fine lines and improve skin texture through medical-grade retinoid therapy.

Hyperpigmentation

Brightening Complex Protocol

Target dark spots and uneven tone with clinical-strength brightening agents.

Acne Management

Clinical Acne Control Protocol

Clear active breakouts and prevent future acne with medical-grade formulations.

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Advanced Retinol Protocol

Week 1-2

Skin Preparation

Begin with gentle cleanser and barrier repair serum to prepare skin for active treatment.

Week 3-4

Retinol Introduction

Introduce 0.25% retinol 2-3 times per week, monitoring for tolerance.

Week 5-8

Gradual Increase

Increase frequency to nightly application as tolerated.

Week 9-12

Strength Advancement

Progress to 0.5% retinol formulation for enhanced results.

Week 12+

Maintenance Phase

Continue nightly application with quarterly clinical assessments.

Brightening Complex Protocol

Week 1-2

Assessment & Prep

Clinical photography and baseline assessment with gentle exfoliation.

Week 3-6

Active Treatment

Apply brightening serum with hydroquinone alternative twice daily.

Week 7-10

Enhancement Phase

Add vitamin C serum in morning routine for synergistic effects.

Week 11-12

Progress Evaluation

Clinical reassessment and protocol adjustment as needed.

Week 12+

Long-term Maintenance

Continue maintenance regimen with SPF 50+ daily protection.

Clinical Acne Control Protocol

Week 1-2

Barrier Restoration

Gentle cleansing and barrier support to prepare for active treatment.

Week 3-4

Benzoyl Peroxide Introduction

Begin 2.5% benzoyl peroxide application every other evening.

Week 5-8

Salicylic Acid Addition

Add 2% salicylic acid serum in morning routine for pore refinement.

Week 9-12

Retinoid Integration

Introduce retinoid 2-3 times weekly for enhanced cell turnover.

Week 12+

Maintenance & Prevention

Continue full protocol with monthly clinical monitoring.