Skinbetter Science
SkinBetter BioRewind® Skin Health Dietary Supplement
SkinBetter BioRewind® Skin Health Dietary Supplement
“My goal is to provide my patients with the highest quality, scientifically-backed solutions to support their wellness journey. Each product is formulated with that same commitment to excellence and efficacy.”
Learn more about Dr. Piazza →Couldn't load pickup availability
Address Skin Aging From the Inside — SkinBetter BioRewind®
BioRewind® Skin Health Dietary Supplement targets glycation, a driver of skin aging that topicals cannot reach. When excess sugar molecules bind to proteins in the body, they form Advanced Glycation End Products (AGEs) — and AGEs damage the collagen and elastin that keep skin firm and smooth. BioRewind works on that process internally, using skinbetter's exclusive CORExtract™ rosemary biotechnology.
⚠️ Final stock — we are not restocking BioRewind. Three boxes remain. Available through the Shop app only.
✨ Key Benefits:
- Targets glycation and the formation of AGEs at the source
- Helps reduce the appearance of skin redness
- Helps reduce the look of dullness for a brighter complexion
- Helps smooth the appearance of rough, uneven texture
- Works from within — complements, rather than replaces, a topical routine
How to Use: Take 2 capsules daily with meals. skinbetter's clinically tested regimen steps down over time — Month 1: 2 capsules three times daily. Month 2: 2 capsules twice daily. Month 3 onward: 1 capsule twice daily.
What Glycation Actually Is
Most skincare addresses damage at the surface — sun exposure, dryness, cell turnover. Glycation happens underneath all of that. Sugar molecules circulating in the bloodstream attach themselves to nearby proteins, and collagen and elastin are among the most vulnerable, because the body replaces them slowly. Once glycated, those fibers stiffen and yellow, which shows up as dullness, a loss of bounce, and texture that no serum quite fixes. That is the gap an oral supplement can close, and it is why BioRewind is designed to sit alongside a topical routine rather than compete with one.
Key Ingredients
- CORExtract™ — skinbetter's proprietary rosemary extract, standardized for Rosmarinic Acid, the ingredient at the center of the clinical work.
- Biotin — supports skin, hair and nail health.
- Zinc Gluconate — a mineral that supports normal skin function.
skinbetter's Clinical Results
In a 12-week trial of 52 patients conducted by skinbetter science:
- At 8 weeks — 12% reduction in redness, 23% reduction in dullness, 26% improvement in texture
- At 12 weeks — 14% reduction in redness, 28% reduction in dullness, 30% improvement in texture
Results reported by skinbetter science. Individual results may vary.
Who It's For
A strong fit if your skin looks dull or sallow despite a solid topical routine, if you are seeing texture and crepiness that serums have not shifted, or if you are already investing in in-office treatments and want to support the result internally. Worth knowing that glycation accelerates with a higher-sugar diet, so this pairs sensibly with dietary changes rather than substituting for them.
How to Work It Into Your Routine
Take it with meals — the capsules are better tolerated with food, and the stepped regimen front-loads the dose during the first two months when the clinical change was measured. Give it the full eight weeks before judging; this is not a product with a visible next-day effect. It layers with any topical routine, including retinoids and acids, since it works internally.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Speak with your physician before beginning any supplement, particularly if you are pregnant, nursing, or taking medication.
Curated by the team at The Piazza Center for Plastic Surgery & Advanced Skincare in Austin, Texas.

The Piazza Protocols
Hand-selected by board-certified plastic surgeon Dr. Rocco Piazza, MD, FACS, to meet the highest standards in medical-grade skincare.
🛡️ Board-Certified Plastic Surgeon
🔬 Backed by Clinical Expertise & Research
Advanced Retinol Protocol
Reduce fine lines and improve skin texture through medical-grade retinoid therapy.
Brightening Complex Protocol
Target dark spots and uneven tone with clinical-strength brightening agents.
Clinical Acne Control Protocol
Clear active breakouts and prevent future acne with medical-grade formulations.
Advanced Retinol Protocol
Skin Preparation
Begin with gentle cleanser and barrier repair serum to prepare skin for active treatment.
Retinol Introduction
Introduce 0.25% retinol 2-3 times per week, monitoring for tolerance.
Gradual Increase
Increase frequency to nightly application as tolerated.
Strength Advancement
Progress to 0.5% retinol formulation for enhanced results.
Maintenance Phase
Continue nightly application with quarterly clinical assessments.
Brightening Complex Protocol
Assessment & Prep
Clinical photography and baseline assessment with gentle exfoliation.
Active Treatment
Apply brightening serum with hydroquinone alternative twice daily.
Enhancement Phase
Add vitamin C serum in morning routine for synergistic effects.
Progress Evaluation
Clinical reassessment and protocol adjustment as needed.
Long-term Maintenance
Continue maintenance regimen with SPF 50+ daily protection.
Clinical Acne Control Protocol
Barrier Restoration
Gentle cleansing and barrier support to prepare for active treatment.
Benzoyl Peroxide Introduction
Begin 2.5% benzoyl peroxide application every other evening.
Salicylic Acid Addition
Add 2% salicylic acid serum in morning routine for pore refinement.
Retinoid Integration
Introduce retinoid 2-3 times weekly for enhanced cell turnover.
Maintenance & Prevention
Continue full protocol with monthly clinical monitoring.
Find Your Solution
Discover medical-grade skincare tailored to your specific concerns
Surgeon-Curated Systems
EXO HAIR™ Red Light LED Hair Brush
Plastic Surgery Scar Healing Kit