5 Things to Know: Plated Intense Exosome Serum | Dr. Rocco Piazza
By Dr. Rocco Piazza, MD
In the world of regenerative aesthetics, few innovations have caused as much of a stir as Plated Intense Growth Factor Serum. As we move away from simply "covering up" signs of aging and toward "biohacking" our skin’s natural ability to repair itself, this serum has become a cornerstone of the protocols we design here at The Piazza Center.
1. Great for Pigmentation
One of the most frequent inquiries we receive is regarding stubborn brown spots and redness. Plated Intense uses Renewosome™ technology to address molecular aging at the source.
Unlike harsh chemical brighteners, it signals the skin to clear out damaged cells and accelerate healthy turnover. Patients typically report a visible reduction in sun damage and vascular redness within just six weeks.
2. Powerful Signaling Messengers
These aren't just generic growth factors. Plated features platelet-derived exosomes—the body's natural "first responders." These microscopic delivery vehicles carry proteins and signaling molecules deep into the dermis.
This triggers your fibroblasts to resume the production of collagen and elastin, acting as a biological "reset" for tired or aging skin cells.
"Exosomes are the future of Biohacking Beauty. Plated Intense is the most sophisticated topical we offer for cellular transformation."
— Dr. Rocco Piazza
3. The "Serum-First" Rule
To maximize the efficacy of Renewosome™ technology, Plated Intense must be applied to clean, dry skin. Once the serum absorbs (1-2 minutes), you must "lock in" the messengers with a restorative cream.
Recommended "Sealant" Pairers:
Revision Skincare® Barrier Pro™
Protects the skin’s microbiome while sealing in growth factors.
Shop Now
Exoceuticals EXO Elevate
Formulated with Mesenchymal Exosomes and Copper Peptides for ultimate firming.
Shop Now4. Advanced Regenerative Support
For those looking for an extra-strength boost, we often recommend layering your regimen with Exoceuticals EXO Plus. This concentrate works synergistically with the platelet-derived signaling of Plated to maximize the skin's density and luminosity.
Plated Intense is your high-concentration "jumpstart" for 6-12 weeks, after which most patients transition to Plated Daily.
5. The Ultimate Post-Procedure Repair
After treatments like HALO™, BBL®, or microneedling, your skin is in a state of repair. Plated Intense accelerates the closing of micro-channels and slashes downtime.
Alastin Skin Nectar
Seal with this occlusive to prevent water loss and ensure exosome penetration.
Shop Nectar
Acne-Prone? Plated Calm
Clinical FAQ
No. The Renewosome™ technology ensures these exosomes are shelf-stable at room temperature.
Yes. Apply Plated Intense first to clean, dry skin. Wait 2 minutes for it to dry completely before applying your retinoids.
The Science of Cellular Signaling
At The Piazza Center, we prioritize treatments backed by rigorous peer-reviewed data. To understand why Plated Intense and our recommended sealants like Exoceuticals are so effective, we must look at the two primary types of exosomes used in regenerative aesthetics:
1. Platelet-Derived Exosomes (Plated Skin Science)
Platelets are the body's natural signaling centers for wound healing. Research published in the National Library of Medicine demonstrates that platelet-derived exosomes significantly accelerate tissue repair by promoting the migration of fibroblasts and increasing the synthesis of Type I Collagen.
2. Mesenchymal Stem Cell (MSC) Exosomes (Exoceuticals)
While platelet exosomes focus on "rescue and repair," Mesenchymal exosomes—found in Exoceuticals EXO Elevate—are masters of anti-inflammation. According to studies in Nature: Regenerative Medicine, MSC exosomes modulate the skin's immune response, making them the ideal partner for calming the skin after energy-based treatments like HALO™ or BBL®.
"By layering these two distinct exosome sources, we provide the skin with a complete vocabulary of regenerative messages—one to jumpstart repair and one to maintain a youthful, calm environment." — Dr. Rocco Piazza
